Rev-Erbα/NR1D1 polyclonal antibody

Product Specifications

Background

This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) . This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

NR1D1; EAR1; THRA1; THRAL; ear-1; hRev; nuclear receptor subfamily 1 group D member 1

Swiss Prot

P20393

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human Rev-Erbα/NR1D1 (NP_068370.1) .

Conjugation

Unconjugated

Applications

WB, IHC, IF/ICC

Dilution

WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .