IRE1a-IN-2

IRE1a-IN-2 (Compound 30) is an IRE1α inhibitor, with an IC50 of over than 200 nM for XBP1 mRNA. IRE1a-IN-2 can be used for the research of cancer[1].

Product Specifications

CAS Number

[3033375-24-2]

UNSPSC

12352005

Target

IRE1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ire1a-in-2.html

Smiles

CC1=C(C(OC2=C1C3=C(C(O)=C2C=O)OCCC3)=O)CC(N4CCSC4)=O

Molecular Formula

C19H19NO6S

Molecular Weight

389.42

References & Citations

[1]Jin ZS, et al. Novel tricyclic heterocyclic aldehyde compound for inhibiting IRE1α and pharmaceutical composition containing the compound. WO2024072110A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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