IRE1a-IN-2
Product Specifications
UNSPSC Description
IRE1a-IN-2 (Compound 30) is an IRE1α inhibitor, with an IC50 of over than 200 nM for XBP1 mRNA. IRE1a-IN-2 can be used for the research of cancer[1].
Target Antigen
IRE1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ire1a-in-2.html
Smiles
CC1=C(C(OC2=C1C3=C(C(O)=C2C=O)OCCC3)=O)CC(N4CCSC4)=O
Molecular Weight
389.42
References & Citations
[1]Jin ZS, et al. Novel tricyclic heterocyclic aldehyde compound for inhibiting IRE1α and pharmaceutical composition containing the compound. WO2024072110A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158393/IRE1a-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158393/
Clinical Information
No Development Reported
CAS Number
3033375-24-2
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