IRE1a-IN-2
IRE1a-IN-2 (Compound 30) is an IRE1α inhibitor, with an IC50 of over than 200 nM for XBP1 mRNA. IRE1a-IN-2 can be used for the research of cancer[1].
Product Specifications
CAS Number
[3033375-24-2]
UNSPSC
12352005
Target
IRE1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ire1a-in-2.html
Smiles
CC1=C(C(OC2=C1C3=C(C(O)=C2C=O)OCCC3)=O)CC(N4CCSC4)=O
Molecular Formula
C19H19NO6S
Molecular Weight
389.42
References & Citations
[1]Jin ZS, et al. Novel tricyclic heterocyclic aldehyde compound for inhibiting IRE1α and pharmaceutical composition containing the compound. WO2024072110A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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