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TC-O 9311

TC-O 9311 is a potent orphan G protein-coupled receptor 139 (GPR139) agonist with an EC50 of 39 nM[1].

Product Specifications

CAS Number

[444932-31-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

GPR139

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tc-o-9311.html

Purity

99.83

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NNC(NC1=C2C=CC=CC2=CC=C1)=O)C3=CC(OC)=CC(OC)=C3

Molecular Formula

C20H19N3O4

Molecular Weight

365.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Shi F, et al. Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139. ACS Med Chem Lett. 2011 Feb 28;2 (4) :303-6.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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