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Phospho-STAT3 (Ser727) monoclonal antibody

Product Specifications

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.

CAS Number

9007-83-4

Structure Composition

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Product Name Alternative

STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor

Swiss Prot

P40763

Reactivity

Human, Rat

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser727 of human STAT3

Conjugation

Unconjugated

Applications

WB, ICC/IF

Dilution

WB: 1/500-1/1000 IF: 1/50-1/200

Purity

Affinity Purified

Modification

Phosphorylated

Molecular Weight

Calculated MW: 88 kDa; Observed MW: 88 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of Phospho-STAT3 in Jurkat, C6, Hela lysates using Phospho-STAT3 antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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