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ATG7 Monoclonal Antibody

Product Specifications

Background

ATG7 (Autophagy Related 7) is a Protein Coding gene. Among its related pathways are Autophagy Pathway and Innate Immune System. GO annotations related to this gene include protein homodimerization activity and ubiquitin activating enzyme activity. This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.

Abbreviation

ATG7

UniProt

O95352

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Protein of ATG7

Target

1810013K23Rik; Apg 7; APG7 autophagy 7 like; APG7 autophagy 7-like (S. cerevisiae) ; APG7 like; APG7; S. cerevisiae; homolog of; APG7-like; APG7L; ATG 7; ATG12-activating enzyme E1 ATG7; ATG7; ATG7 autophagy related 7 homolog (S. cerevisiae) ; ATG7 autophagy related 7 homolog; ATG7; Atg7l; Autophagy 7; S. cerevisiae; homolog of; Autophagy related protein 7; Autophagy-related 7 (yeast) ; Autophagy-related protein 7; DKFZp434N0735; GSA 7; GSA7; hAGP7; Ubiquitin activating enzyme E1 like protein; Ubiquitin-activating enzyme E1-like protein; Ubiquitin-like modifier-activating enzyme ATG7

Clonality

Monoclonal

Clone

Clone:1A1

Conjugation

Unconjugated

Applications

IHC-p; IF

Field of Research

Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction

Purification

Protein A purification

Concentration

1 mg/mL

Dilution

IHC 1:50-300; IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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