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JNK1/3 polyclonal antibody

Product Specifications

Background

The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, by growth factors and GPCR agonists. As with the other MAPKs, the core signaling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kinases (MLKs), which phosphorylate and activate MKK4/7.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Product Name Alternative

C-Jun N-terminal kinase 3; FLJ12099; FLJ33785; JNK1; JNK3; JNK3 alpha protein kinase; JNK3A; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10

Swiss Prot

P45983/P53779

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human JNK1/JNK3

Conjugation

Unconjugated

Applications

WB, IP

Dilution

WB: 1/500-1/1000 IP: 1/20

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 48 kDa; Observed MW: 46,54 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of JNK1/JNK3 in HeLa lysates using JNK1/3 antibody.

Host or Source

Rabbit

Available Sizes

Curated Selection

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