NR2C2 Mouse Monoclonal Antibody [Clone ID: LBI4B1]
Product Specifications
Background
This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Synonyms
TAK1; TR4
Gene Name
Nuclear receptor subfamily 2 group C member 2
Gene ID
7182
UniProt
P49116
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NR2C2
Overview
NR2C2 mouse monoclonal antibody, clone LBI4B1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7182
Uniprot URL
https://www.uniprot.org/uniprot/P49116
Curated Selection
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