Histone H1.8 polyclonal antibody
Product Specifications
Background
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling .
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
H1.8; H1oo; osH1
Swiss Prot
Q8IZA3
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human Histone H1. AA range:131-180
Conjugation
Unconjugated
Applications
IHC-P, IHC-F, ICC/IF, ELISA
Dilution
IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Purity
Affinity Purified
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Immunofluorescence analysis of Histone H1.8 in HeLa cells using Histone H1.8 antibody. Sample with blocking peptide on the right.
Host or Source
Rabbit
Available Sizes
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