PSPN polyclonal antibody
Product Specifications
Background
The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
PSPN; Persephin; PSP
Swiss Prot
O60542
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human PSPN. AA range:101-150
Conjugation
Unconjugated
Applications
WB, ELISA
Dilution
WB: 1/500-1/1000 ELISA: 1/10000
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 17 kDa; Observed MW: 17 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of PSPN in 293 lysates using PSPN antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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