RPE65 Rabbit monoclonal antibody
Product Specifications
Background
Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
LCA2; mRPE65; p63; rd12; Retinal pigment epithelium specific 61 kDa protein; RP20; RPE65; sRPE65
Swiss Prot
Q16518
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human RPE65
Conjugation
Unconjugated
Applications
WB IP
Dilution
WB 1:500~1:2000 IP 1:50
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
61kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RPE65 Antibody detects endogenous levels of total RPE65
Applications Notes
Western blot analysis of RPE65 expression in mouse eyeball lysate.
Host or Source
Rabbit
Available Sizes
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