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M6PR Rabbit monoclonal antibody

Product Specifications

Background

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

IGF2R; CI Man-6-P receptor; CI-MPR; M6PR; MPR 300; Insulin-like growth factor 2 receptor; M6P/IGF2R; CD222

Swiss Prot

P11717

Reactivity

Human Mouse Rat

Immunogen

A synthesized peptide derived from human M6PR

Conjugation

Unconjugated

Applications

WB IHC ICC/IF IP FC

Dilution

WB 1:5000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:100

Purity

Affinity-chromatography

Modification

Unmodified

Molecular Weight

274kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

M6PR Antibody detects endogenous levels of total M6PR

Applications Notes

Western blot analysis of extracts of M6PR expression in Jurkat cell lysate.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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