M6PR Rabbit monoclonal antibody
Product Specifications
Background
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
IGF2R; CI Man-6-P receptor; CI-MPR; M6PR; MPR 300; Insulin-like growth factor 2 receptor; M6P/IGF2R; CD222
Swiss Prot
P11717
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human M6PR
Conjugation
Unconjugated
Applications
WB IHC ICC/IF IP FC
Dilution
WB 1:5000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:100
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
274kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
M6PR Antibody detects endogenous levels of total M6PR
Applications Notes
Western blot analysis of extracts of M6PR expression in Jurkat cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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