eIF1A Recombinant Rabbit Monoclonal Antibody [JE64-63]
Eukaryotic translation initiation factor 1A, X-chromosomal (eIF1A) is a protein that in humans is encoded by the EIF1AX gene. This gene encodes an essential eukaryotic translation initiation factor. The protein is a component of the 43S pre-initiation complex (PIC), which mediates the recruitment of the small 40S ribosomal subunit to the 5' cap of messenger RNAs. eIF1A is a small protein (17 kDa in budding yeast) and a component of the 43S preinitiation complexes (PIC). eIF1A binds near the ribosomal A-site, in a manner similar to the functionally related bacterial counterpart IF1. Mutations in this gene have been recurrently seen associated to cases of uveal melanoma with disomy 3. eIF1A is mutated in thyroid cancers. EIF1AX has been shown to interact with IPO13.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
EIF1AX
Swiss Prot
P47813 Human, Q8BMJ3 Mouse, Q6VV72 Rat
Cellular Locus
Cytosol.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within human eIF1A aa 51-100/144.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Jurkat cell lysate, HepG2 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, human colon carcinoma tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:400
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 16 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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