NF-κB (p105/p50) Rabbit monoclonal antibody
Product Specifications
Background
NFkB-p105 a transcription factor of the nuclear factor-kappaB (NFkB) group. Undergoes cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of NFkB. NFkB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
NF-kappa-B1; p84/NF-kappa-B1 p98; NFKB1; DNA-binding factor KBF1; EBP-1; NFkB-p50
Swiss Prot
P19838
Reactivity
Human Mouse Rat
Immunogen
A synthesized peptide derived from human NF-κB (p105/p50)
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB 1:500~1:2000 IHC 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
~ 50,105 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NF-κB (p105/p50) Antibody detects endogenous levels of total NF-κB (p105/p50)
Applications Notes
Western blot (WB) analysis of NF-κB (p105/p50) Rabbit monoclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate (30ug) Lane2:Myla2059 whole cell lysate (30ug) Lane3:PC12 whole cell lysate (30ug) Lane4:3T3-L1 whole cell lysate (30ug)
Host or Source
Rabbit
Available Sizes
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