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CCR9 Recombinant Rabbit Monoclonal Antibody [JE00-35]

The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Specifications

Product Name Alternative

C C chemokine receptor D6 antibody C C chemokine receptor type 9 antibody C C CKR 9 antibody C-C chemokine receptor type 9 antibody C-C CKR-9 antibody CC Chemokine receptor CCR10 antibody CC CKR 9 antibody CC-CKR-9 antibody CCBP2 antibody CCCKR9 antibody CCR 9 antibody CCR-9 antibody Ccr9 antibody CCR9_HUMAN antibody CDw199 antibody CDw199 antigen antibody Chemokine (C C motif) receptor 9 antibody Chemokine (C C motif) receptor 9, isoform CRA_a antibody Chemokine (C-C motif) receptor 9 isoform A antibody Chemokine (C-C motif) receptor 9 isoform B antibody Chemokine C C motif receptor 9 antibody Chemokine C C receptor 10 antibody Chemokine CC Motif Receptor 9 antibody Chemokine receptor CCR 9 antibody Chemokine receptor CCR9 antibody Chemokine-binding protein D6 antibody Cmkbr10 antibody CMKBR9 antibody G protein coupled receptor 28 antibody G-protein coupled receptor 28 antibody GPR 28 antibody GPR 9 6 antibody GPR-9-6 antibody GPR28 antibody GPR96 antibody OTTHUMP00000164653 antibody OTTHUMP00000164654 antibody

Abbreviation

C-C chemokine receptor type 9 C-C CKR-9; CC-CKR-9; CCR-9 G-protein coupled receptor 28 GPR-9-6 CDw199 CCR9 GPR28

Swiss Prot

P51686 Human, Q9WUT7 Mouse,

Cellular Locus

Cell membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within Human CCR9 aa 1-100 / 369.

Isotype

IgG

Clone

JE00-35

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB

Positive Control

A549 cell lysate, Jurkat cell lysate, HepG2 cell lysate, mouse thymus tissue lysate, rat lung tissue lysate, rat thymus tissue lysate.

Concentration

1 mg/mL

Dilution

WB: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 42 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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