Nicotinamide (Hydrochloride)
Nicotinamide Hydrochloride is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM) . Nicotinamide Hydrochloride also inhibits SIRT1. Nicotinamide Hydrochloride increases cellular NAD+, ATP, ROS levels. Nicotinamide Hydrochloride inhibits tumor growth and improves survival. Nicotinamide Hydrochloride also has anti-HBV activity[1][2][3][4].
Product Specifications
CAS Number
25334-23-0
Product Name Alternative
Niacinamide (Hydrochloride) ; Nicotinic acid amide (Hydrochloride)
UNSPSC
12352005
Target
Endogenous Metabolite; HBV; Sirtuin
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/nicotinamide-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CN=C1)N.[H]Cl
Molecular Formula
C6H7ClN2O
Molecular Weight
158.59
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Human Endogenous Metabolite; SIRT1; SIRT2
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
UGP1 CRISPRa sgRNA lentivector (set of three targets)(Human)
