Fmoc-3VVD-OH (GMP)
Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[863971-44-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
GMP Small Molecules
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-3vvd-oh-gmp.html
Solubility
10 mM in DMSO
Smiles
CN([C@H]([C@H](OC)CC(O)=O)[C@@H](C)CC)C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C)=O)=O
Molecular Formula
C36H51N3O7
Molecular Weight
637.81
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Siew Schleyer, et al. Auristatin-related compounds, conjugated auristatin-related compounds, and methods of use thereof. WO2021142029A1.
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
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