BW A868C

BW A868C, a hydantoin compound, is a BW245C structural analogue. BW A868C is a selective and potent competitive prostaglandin D2 (PGD2) antagonist. BW A868C has no effect on other prostaglandin receptors (IP, EP1, EP2, TP and FP) [1].

Product Specifications

CAS Number

[118675-50-6]

UNSPSC

12352005

Hazard Statement

H225, H319, H350

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bw-a868c.html

Concentration

21.76 mM * 100 μL in Ethanol

Purity

99.00

Solubility

10 mM in DMSO

Smiles

O=C(CCCCCCC1C(N(CC2=CC=CC=C2)C(N1NCC(C3CCCCC3)O)=O)=O)O

Molecular Formula

C25H37N3O5

Molecular Weight

459.58

Precautions

H225, H319, H350

References & Citations

[1]H Giles, et al. The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist. Br J Pharmacol. 1989 Feb;96 (2) :291-300.