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HDAC/NAMPT-IN-1

HDAC/NAMPT-IN-1 (compound 39h) is a dual inhibitor of HDAC and NAMPT with IC50 values of 0.72-37081 nM and 1618 nM[1].

Product Specifications

CAS Number

2898381-63-8

UNSPSC

12352005

Target

HDAC; NAMPT

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hdac-nampt-in-1.html

Solubility

10 mM in DMSO

Smiles

CCCNNC(C1=CC=C(CNC(C2=CC3=CN=CC=C3N2)=O)C=C1)=O

Molecular Formula

C19H21N5O2

Molecular Weight

351.40

References & Citations

[1]Kairui Yue, et al. HDAC/NAMPT dual inhibitors overcome initial drug-resistance in p53-null leukemia cells. Eur J Med Chem. 2024.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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