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Acetylene-PEG3-MMAF-OMe

Acetylene-PEG3-MMAF-OMe (LCB14-0536) is a protein-active agent conjugate. Acetylene-PEG3-MMAF-OMe can be recognized by isoprenoid transferase[1]. Acetylene-PEG3-MMAF-OMe is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

1411977-91-7

Product Name Alternative

LCB14-0536

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/acetylene-peg3-mmaf-ome.html

Solubility

10 mM in DMSO

Smiles

COC([C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(COCCOCCOCC#C)=O)=O)=O)=O)OC)=O)=O

Molecular Formula

C49H79N5O12

Molecular Weight

930.18

References & Citations

[1]Yongzu KIM, et al. Protein-active agent conjugates and method for preparing the same. Patent WO2012153193A2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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