Recombinant Human CD52 (C-Fc-Avi) Biotinylated
Product Specifications
Background
CD52, also known as CAMPATH-1 antigen, HE5, and gp20, is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocycte-derived dendritic cells, eosinophils, and neutrophils, as well as on mature spermatozoa and epithelial cells lining the male genital tract. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.
Abbreviation
CD52
Synonyms
CAMPATH-1; CAMPATH-1 antigen; CD52; CD52 antigen; CD52 molecule; CDw52; Epididymal secretory protein E5; HEL-S-171mP; He5; Human epididymis-specific protein 5
UniProt
P31358
Accession Number
P31358
Expression System
HEK293 Cells
Conjugation
Biotinylated
Tag
C-Fc-Avi
Sequence
Gly25-Ser36
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/krgvyp
Product MSDS
https://789.bio/eb/9mbLCS
Calculated Molecular Weight
30.2 kDa
Observed Molecular Weight
38-50 kDa
Species
Human
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
