EGFR-IN-84
EGFR-IN-84 (Compound 6g) is an EGFR inhibitor (IC50: 24 nM) . EGFR-IN-84 inhibits A549 cell growth (IC50: 1.537 μM) . EGFR-IN-84 can be used for research of lung cancer[1].
Product Specifications
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-84.html
Solubility
10 mM in DMSO
Smiles
O=C(CSC1=NN=C(NC2=CC=CC=C2)S1)N(C(C3=CC=C([N+]([O-])=O)C=C3)C4)N=C4C5=CC=CC=C5
Molecular Formula
C25H20N6O3S2
Molecular Weight
516.59
References & Citations
[1]Kurban B, et al. Synthesis and Anticancer Activities of Pyrazole-Thiadiazole-Based EGFR Inhibitors. ACS Omega. 2023 Aug 17;8 (34) :31500-31509.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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