Recombinant SARS-CoV-2 ORF7a protein
Product Specifications
Background
Plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. Acts by binding to BST2 thereby interfering with its glycosylation. May suppress small interfering RNA (siRNA) . May bind to host ITGAL, thereby playing a role in attachment or modulation of leukocytes.
Synonyms
7a; Accessory protein 7a; Protein U122; Protein X4
UniProt
P0DTC7
Accession Number
YP_009724395.1
Expression System
E. coli
Tag
N-His
Sequence
Glu16-Tyr97
Endotoxin
Please contact us for more information.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
12.1 kDa
Formulation
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
Species
SARS-CoV-2
Available Sizes
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