3′-O-[ (1,1-Dimethylethyl) dimethylsilyl]-2′-O-methyluridine
3′-O-[ (1,1-Dimethylethyl) dimethylsilyl]-2′-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
Product Specifications
CAS Number
[171268-84-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-o-1-1-dimethylethyl-dimethylsilyl-2-o-methyluridine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O1
Molecular Formula
C16H28N2O6Si
Molecular Weight
372.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20 (5) :218-25.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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