Vitamin D3-d3

Vitamin D3-d3 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

Product Specifications

CAS Number

[80666-48-4]

Product Name Alternative

Cholecalciferol-d3; Colecalciferol-d3

UNSPSC

12352211

Hazard Statement

H300+H310, H372

Target

Bacterial; Endogenous Metabolite; Isotope-Labeled Compounds; VD/VDR

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease

Purity

98.45

Solubility

Ethanol : 1 mg/mL (ultrasonic; warming)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])/C(CCC1)=C/C([2H])=C3\C(CC[C@@H](C3)O)=C([2H])/[2H]

Molecular Formula

C27H41D3O

Molecular Weight

387.66

Precautions

H300+H310, H372

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Yoshioka H, et al. Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice. PLoS One. 2017 Apr 27;12 (4) :e0176524.