(γ-AmNS) UTP (trisodium)
(γ-AmNS) UTP (trisodium) is a fluorescent derivative of UTP and enables the detection of RNA polymerase activity. Incorporation of UMP in RNA results in the release of γ-AmNS-PPi, which has higher intrinsic fluorescence than (γ-AmNS) UTP. (γ-AmNS) UTP (trisodium) can be used for antibacterial and antituberculosis agents study[1].
Product Specifications
UNSPSC
12352005
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Infection
Smiles
O=C(N(C=C1)[C@@H]2O[C@H](COP(OP(OP(NC3=CC=CC4=C3C=CC=C4S(O)(=O)=O)(O[Na])=O)(O[Na])=O)(O[Na])=O)[C@@H](O)[C@H]2O)NC1=O
Molecular Formula
C19H19N3Na3O17P3S
Molecular Weight
755.32
References & Citations
[1]Bhat J, et al. High-throughput screening of RNA polymerase inhibitors using a fluorescent UTP analog. J Biomol Screen. 2006 Dec;11 (8) :968-76.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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