ASK1-IN-4

ASK1-IN-4 (Compound 17) is an ASK1 inhibitor (IC50=0.2 μM). ASK1-IN-4 interacts with ATP-binding site of ASK1[1].

Apoptosis; MAP3K

Reference compound

Apoptosis;MAPK/ERK Pathway

COVID-19-immunoregulation

Cancer; Inflammation/Immunology

https://www.medchemexpress.com/ask1-in-4.html

10 mM in DMSO

BrC(C=C1)=CC=C1C2=CC=C(O2)/C=C3C(N(C(S/3)=S)CCCC(O)=O)=O

452.34

[1]Starosyla SA,et al. ASK1 pharmacophore model derived from diverse classes of inhibitors. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4418-4423.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-153761/ASK1-IN-4-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-153761/

No Development Reported

1427538-26-8