Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

UC-781

UC-781 (NSC 675186) is a highly potent and selective nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with an IC50 value of 5 nM. UC-781 is stable under low PH or various temperatures conditions. UC-781 has antiviral activity and resistance[1][2][3].

Product Specifications

CAS Number

178870-32-1

Product Name Alternative

NSC 675186

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/uc-781.html

Solubility

10 mM in DMSO

Smiles

S=C(C1=C(C)OC=C1)NC2=CC=C(Cl)C(OC/C=C(C)/C)=C2

Molecular Formula

C17H18ClNO2S

Molecular Weight

335.85

References & Citations

[1]Balzarini J, et al. Preclinical studies on thiocarboxanilide UC-781 as a virucidal agent. AIDS. 1998 Jul 9;12 (10) :1129-38. |[2]Van Herrewege Y, et al. In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides. Antimicrob Agents Chemother. 2004 Jan;48 (1) :337-9. |[3]Balzarini J, et al. Highly favorable antiviral activity and resistance profile of the novel thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of human immunodeficiency virus type 1 replication. Mol Pharmacol. 1996 Aug;50 (2) :394-401. |[4]Fletcher P, et al. The nonnucleoside reverse transcriptase inhibitor UC-781 inhibits human immunodeficiency virus type 1 infection of human cervical tissue and dissemination by migratory cells. J Virol. 2005 Sep;79 (17) :11179-86.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

HIV-1

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

SMQ-03-20
HY-162954 1 Each

SMQ-03-20

Sign In for Pricing
View Details
Anti-Zebrafish PFN2a/b Antibody Picoband®
AZQ6AZA1-carrier-free 100 µg/Vial

Anti-Zebrafish PFN2a/b Antibody Picoband®

Sign In for Pricing
View Details
Monkey Anti-Ovary Antibody, AOAb ELISA Kit
MBS7262482-01 48 Well

Monkey Anti-Ovary Antibody, AOAb ELISA Kit

Sign In for Pricing
View Details
Monkey Anti-Ovary Antibody, AOAb ELISA Kit
MBS7262482-02 96 Well

Monkey Anti-Ovary Antibody, AOAb ELISA Kit

Sign In for Pricing
View Details
Monkey Anti-Ovary Antibody, AOAb ELISA Kit
MBS7262482-03 5x 96 Well

Monkey Anti-Ovary Antibody, AOAb ELISA Kit

Sign In for Pricing
View Details
Monkey Anti-Ovary Antibody, AOAb ELISA Kit
MBS7262482-04 10x 96 Well

Monkey Anti-Ovary Antibody, AOAb ELISA Kit

Sign In for Pricing
View Details