SMQ-03-20
SMQ-03-20 (compund 4g) is an orally bioavailable, brain-penetrant, selective and potent PDE11A4 inhibitor[1].
Product Specifications
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pde11a4-in-2.html
Smiles
CN1N=CC=C1C2=CC(C3=NN=CS3)=C4C(N(N=C4C)C5=CC=C(C=C5)F)=N2
Molecular Formula
C19H14FN7S
Molecular Weight
391.42
References & Citations
[1]Mahmood SU, et al. First Demonstration of In Vivo PDE11A4 Target Engagement for Potential Treatment of Age-Related Memory Disorders. J Med Chem. 2024 Oct 10;67 (19) :17774-17784.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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