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DRAK1/2-IN-1

DRAK1/2-IN-1 (compound 10e) is an active dual DRAK1 and DRAK2 inhibitor with Kd values of 1 μM and 6 μM, respectively[1].

Product Specifications

CAS Number

1629227-34-4

UNSPSC

12352005

Target

DAPK

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/drak1-2-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1CCCCC1)NC2=CSC3=NC=C(C4=CC(OC)=C(OC)C=C4)C=C32

Molecular Formula

C22H24N2O3S

Molecular Weight

396.50

References & Citations

[1]Gao LJ, et al. Discovery of dual death-associated protein related apoptosis inducing protein kinase 1 and 2 inhibitors by a scaffold hopping approach. J Med Chem. 2014 Sep 25;57 (18) :7624-43.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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