5-Methoxycarbonyl methyl uridine
Methyl 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[29428-50-0]
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-methoxycarbonyl-methyl-uridine.html
Solubility
10 mM in DMSO
Smiles
O=C(N([C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)C=C2CC(OC)=O)NC2=O
Molecular Formula
C12H16N2O8
Molecular Weight
316.26
Precautions
P264-P280-P302+P352-P362+P364
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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