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GCPII-IN-1 (TFA)

GCPII-IN-1 (Compound 2) TFA is a GCPII (also known as PSMA) inhibitor scaffold with a Ki of 44.3 nM. GCPII-IN-1 TFA can be used in the research of prostate cancer[1].

Product Specifications

CAS Number

[1269794-89-9]

UNSPSC

12352211

Hazard Statement

H302, H315, H319

Target

Carboxypeptidase; PSMA

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gcpii-in-1-tfa.html

Purity

99.58

Solubility

H2O : 160 mg/mL (ultrasonic)

Smiles

OC(C(F)(F)F)=O.NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O

Molecular Formula

C14H22F3N3O9

Molecular Weight

433.33

Precautions

H302, H315, H319

References & Citations

[1]Jan Tykvart, et al. Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg Med Chem. 2014 Aug 1;22 (15) :4099-108.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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