Tubulin inhibitor 31

Tubulin inhibitor 31 is a potent tubulin inhibitor with an IC50 value of 4 μM. Tubulin inhibitor 31 shows anti-proliferative activity. Tubulin inhibitor 31 inhibits the HUVEC migration[1].

Product Specifications

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/tubulin-inhibitor-31.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C(C=C1)CN2C=C(C3=C2C=CC=C3)C4=CC=C(C=C4)O

Molecular Formula

C22H19NO2

Molecular Weight

329.39

References & Citations

[1]Prudhomme V, et al. Design, synthesis and biological evaluation of conformationnally-restricted analogues of E7010 as inhibitors of tubulin assembly (ITA) and vascular disrupting agents (VDA) . Eur J Med Chem. 2022 Dec 15;244:114809.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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