Antitubercular agent-35
Antitubercular agent-35 (compound 42l) is an antitubercular agent. Antitubercular agent-35 inhibits the growth of MtbH37Rv and M. Marinum with MIC90 values of 1.25 and 2 μg/mL, respectively. Antitubercular agent-35 shows the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent-35 can be used for the research of tuberculosis[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitubercular-agent-35.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NOC(C2=CSC(NC3=CC=C(C=C3)Cl)=N2)=C1)NC4=CC=CC=C4
Molecular Formula
C19H13ClN4O2S
Molecular Weight
396.85
References & Citations
[1]Girardini M, et al. Expanding the knowledge around antitubercular 5- (2-aminothiazol-4-yl) isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization. Eur J Med Chem. 2023 Jan 5;245 (Pt 2) :114916.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
