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SIBA

SIBA is a synthetic S-adenosylhomocysteine (SAH) analogue that acts as a broad inhibitor of S-adenosylmethionine-dependent transmethylation. It inhibits enzymes like SAH hydrolase and has demonstrated antiviral activity, reversibly blocking herpes simplex virus type 1 (HSV-1) replication in vitro.

Product Specifications

CAS Number

35899-54-8

Product Name Alternative

Chick embryo fibroblasts, 5'-Isobutylthioadenosine, 5'-Deoxy-5'-isobutylthioadenosine, 3 LL, Analog, cancer, HSV, HSV-1, HEp2, Herpes simplex virus, malaria, NucleosideAntimetabolite, Nucleoside Antimetabolite, Nucleoside Antimetabolite/Analog, Parasite, inhibit, Inhibitor, SIBA, SAH, RMS-J1

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology

Purity

99.15% (May vary between batches)

Solubility

DMSO:90 mg/mL (265.17 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.72 mM)

Smiles

CC (C) CSC[C@H]1O[C@H] ([C@H] (O) [C@@H]1O) n1cnc2c (N) ncnc12

Molecular Formula

C14H21N5O3S

Molecular Weight

339.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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