EGFR/CDK2-IN-1
EGFR/CDK2-IN-1 (Compound 3b) is an EGFR/CDK2 inhibitor. EGFR/CDK2-IN-1 shows good cytotoxicity against MCF7 and HepG2 cells. EGFR/CDK2-IN-1 can be used in cancer research[1].
Product Specifications
CAS Number
2841405-96-5
UNSPSC
12352005
Target
CDK; EGFR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-cdk2-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(Br)C=C1)/C=C/C2=CC=C(C3=CC=CC=C3Cl)O2
Molecular Formula
C19H12BrClO2
Molecular Weight
387.65
References & Citations
[1]Altowyan MS, et al. Synthesis, Characterization, and Cytotoxicity of New Spirooxindoles Engrafted Furan Structural Motif as a Potential Anticancer Agent. ACS Omega. 2022 Sep 27;7 (40) :35743-35754.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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