Lamin B2 Mouse Monoclonal Antibody [J9-C4]
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
LMNB2, LMN2
Swiss Prot
Q03252 Human
Cellular Locus
Nucleus lamina.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide within Human Lamin B2 aa 1-50 / 620.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Jurkat cell lysates, human lung cancer tissue.
Concentration
2 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P:1:500-1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 70 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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