PBRM1-BD2-IN-6
Product Specifications
UNSPSC Description
PBRM1-BD2-IN-6 is a potent PBRM1 bromodomain inhibitor with an IC50 value of 0.22 μM. PBRM1-BD2-IN-6 shows antiproliferation activity. PBRM1-BD2-IN-6 has the potential for the research of PBRM1-dependent cancer[1].
Target Antigen
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pbrm1-bd2-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C2=CC=CC(C)=C2C)NC3=C1C(Cl)=CC=C3
Molecular Weight
286.76
References & Citations
[1]Shishodia S, et al. Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. J Med Chem. 2022 Oct 13.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151533/PBRM1-BD2-IN-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151533/
Clinical Information
No Development Reported
CAS Number
2819989-67-6
Curated Selection
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