ICMT-IN-42

ICMT-IN-42 (compound 21) is an inhibitor of ICMT (IC50=0.054 μM) [1].

Product Specifications

CAS Number

[1313602-67-3]

UNSPSC

12352005

Target

ICMT

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/icmt-in-42.html

Solubility

10 mM in DMSO

Smiles

CC1=CC(C)=CC(NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2)=C1

Molecular Formula

C23H31NO

Molecular Weight

337.50

References & Citations

[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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