HIV protease-IN-1
HIV protease-IN-1 (compound 1·succinate) is a potent HIV protease non-peptidic inhibitor, can be used to research AIDS[1].
Product Specifications
CAS Number
[2511547-82-1]
UNSPSC
12352005
Target
HIV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-protease-in-1.html
Solubility
10 mM in DMSO
Smiles
OC(CCC(O)=O)=O.FC(F)(F)C(C)(C)C[C@@]1(C2=CC=C(C3=NN(C4CC4)N=C3)C=C2)C(N(C(N)=N1)[C@@H](C5=CC(C6=NC=NN6C(F)F)=C(C=C5)Cl)COC(NC7(CC7)C(F)F)=O)=O
Molecular Formula
C39H40ClF7N10O7
Molecular Weight
929.24
References & Citations
[1]Michael A. Ischay, et al. Process Development and Scale-Up of a Protease Inhibitor for the Treatment of HIV Featuring the Preparation of a Neopentyl Grignard Reagent and Development of a One-Pot Curtius Reaction. Org. Process Res. Dev. 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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