α-Glucosidase-IN-21

α-Glucosidase-IN-21 (Compound 2B) is a potent, orally active α-glucosidase inhibitor with an IC50 of 2.62 μM. α-Glucosidase-IN-21 shows anti-diabetic activity[1].

Product Specifications

CAS Number

[321686-01-5]

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-21.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=C(C2=NC3=CC=CC=C3SC(C4=CC=C(OC)C(OC)=C4)C2)C=C1

Molecular Formula

C24H23NO2S

Molecular Weight

389.51

References & Citations

[1]Mehmood R, et al. Synthesis of Novel 2, 3-Dihydro-1, 5-Benzothiazepines as α-Glucosidase Inhibitors: In Vitro, In Vivo, Kinetic, SAR, Molecular Docking, and QSAR Studies. ACS Omega, 2022 Aug 17.