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MALT1-IN-11

MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 IC50 of 10-100 nM. MALT1-IN-11 can be used for the research of cancer, autoimmune and inflammatory disorders[1].

Product Specifications

CAS Number

[2812352-99-9]

UNSPSC

12352005

Target

MALT1

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/malt1-in-11.html

Solubility

10 mM in DMSO

Smiles

CC1(C2=C(C=NC3=CC(F)=NN32)[C@H](C1)C(NC4=CN=C(N5N=CC=N5)C(C(F)(F)F)=C4)=O)C

Molecular Formula

C20H16F4N8O

Molecular Weight

460.39

References & Citations

[1]Shulu FENG, et al. Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disoders. Patent. WO2022164789.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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