Farnesylcysteine

Farnesylcysteine (FC) is a competitive inhibitor of ICMT. The fcly mutant has quantitatively low farnesylcysteine (FC) lyase activity and an enhanced response to ABA. Farnesylcysteine induces an ABA hypersensitive phenotype in Arabidopsis thaliana[1].

Product Specifications

CAS Number

[68000-92-0]

UNSPSC

12352211

Target

ICMT

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/farnesylcysteine.html

Solubility

10 mM in DMSO

Smiles

OC([C@@H](N)CSC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=O

Molecular Formula

C18H31NO2S

Molecular Weight

325.51

References & Citations

[1]Huizinga DH et al. Farnesylcysteine lyase is involved in negative regulation of abscisic acid signaling in Arabidopsis. Mol Plant. 2010 Jan;3 (1) :143-55.