TLR4 agonist-1 (TEA)
TLR4 agonist-1 (TEA) (compound 17a) is a potent agonist of Toll-like Receptor 4 (TLR4), and induces the generation of MIP-1β in RAW 264.7 and MM6 cells[1].
Product Specifications
CAS Number
3020639-70-4
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr4-agonist-1-tea.html
Solubility
10 mM in DMSO
Smiles
OC[C@H]1O[C@@H](OC[C@@H](C([O-])=O)NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@H](NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@H](NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@@H]1OP(O)(O)=O.CC[NH+](CC)CC
Molecular Formula
C87H173N4O15P
Molecular Weight
1546.30
References & Citations
[1]Khalaf JK, et al. Diamino Allose Phosphates: Novel, Potent, and Highly Stable Toll-like Receptor 4 Agonists. J Med Chem. 2023;66 (20) :13900-13917.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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