MAO-B-IN-24
MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B (IC50: 1.60 μM) . MAO-B-IN-24 also inhibited MAO-A (22.42 μM) ; at 10 μM concentration, it also reduced AChE and BChE activities to 54.58% and 88.43%[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mao-b-in-24.html
Solubility
10 mM in DMSO
Smiles
O=C1C2(CCCC2)N(CC3=CC=C(C#N)C=C3)C4=CC=CC=C41
Molecular Formula
C20H18N2O
Molecular Weight
302.37
References & Citations
[1]Perumal K, et al. An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their N-benzylated derivatives for inhibition of the activity of monoamine oxidases. RSC Adv. 2023 Aug 22;13 (36) :24925-24935.. .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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