MAOA-IN-1
MAOA-IN-1 (compound 15) is an orally active MAOA inhibitor with cytotoxicity against prostate cancer cells. MAOA-IN-1 has Caco-2 permeability and lower CNS permeability. MAOA-IN-1 can be further used in the research of anti-cancer and anti-inflammatory indications[1].
Product Specifications
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/maoa-in-1.html
Solubility
10 mM in DMSO
Smiles
OC(CN(C)CC#C)COC1=CC(N)=C(Cl)C=C1Cl
Molecular Formula
C13H16Cl2N2O2
Molecular Weight
303.18
References & Citations
[1]Jacobs MR, et al. Synthesis and anti-cancer potential of potent peripheral MAOA inhibitors designed to limit blood:brain penetration. Bioorg Med Chem. 2023 Sep 7;92:117425.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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