FXR antagonist 2
FXR antagonist 2 (compound A-26) is a diarylamide derivative, as well as a moderate FXR antagonist. FXR antagonist 2 can be used in the study of hyperlipidemia and type 2 diabetes[1].
Product Specifications
CAS Number
1660153-21-8
UNSPSC
12352005
Target
FXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fxr-antagonist-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C=C(NC2CCCC2)C=C1Cl)Cl)NC3=CC=C(C(C(C)(C)C)=C3)O
Molecular Formula
C22H26Cl2N2O2
Molecular Weight
421.36
References & Citations
[1]Hu Lihong, et al. Diarylamide derivative, its preparing method and pharmaceutical application: China, CN104341316. 2015-02-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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