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BAY-299

BAY-299 is a potent and selective inhibitor of BRD1 and the second bromodomain of TAF1 (Transcription initiation factor TFIID subunits. BAY-299 has IC50values of 6-67 and 8-13 nM for BRD1 and TAF1 inhibitor, respectively. BAY-299 shows selectivity over other bromodomains (>30-fold over other members of the BRPF family; BRD9 and ATAD2; >300-fold over BRD4) .

Product Specifications

Format

Solid

Molecular Formula

C25H23N3O4

Shipping Conditions

Room Temperature

Storage Conditions

At least 6 months at -20°C.

Calculated Molecular Weight

429.5 Da

CAS Number

2080306-23-4

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