CSF1R-IN-14
CSF1R-IN-14 is an isoindolinone derivative compound. CSF1R-IN-14 is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-14 has the potential for the research of cancer diseases (extracted from patent WO2019134662A1, compound 1) [1].
Product Specifications
CAS Number
[2361378-89-2]
UNSPSC
12352005
Target
C-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/csf1r-in-14.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(NCC2=CN=C(C=C2)C(F)(F)F)=NC=C1C3=C4CNC(C4=C(C=C3)N(C)C)=O
Molecular Formula
C23H22F3N5O
Molecular Weight
441.45
References & Citations
[1]Wenyuan Qian, et al. Heterocyclic compound as csf-1r inhibitor and use thereof. Patent WO2019134662A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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