Antitumor photosensitizer-3
Product Specifications
UNSPSC Description
Antitumor photosensitizer-3 (Compound I) is a chlorin derivative. Antitumor photosensitizer-3 induces tumor cells apoptosis and necrosis under 650 nm laser irradiation. Antitumor photosensitizer-3 exhibits lower skin photo-toxicity than positive reference m-THPC in vivo[1].
Target Antigen
Necroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-photosensitizer-3.html
Solubility
10 mM in DMSO
Smiles
COC(C1(C2/C(N=C(C21)/C(C3=CC=CC=C3)=C4C=C/C(N/4)=C5\C6=CC=CC=C6)=C(C7=CC=CC=C7)/C(N8)=CC=C8/C(C9=CC=CC=C9)=C%10C=CC5=N/%10)C(O)=O)=O
Molecular Weight
730.81
References & Citations
[1]Gao YH, et al. Synthesis and pharmacological evaluation of chlorin derivatives for photodynamic therapy of cholangiocarcinoma. Eur J Med Chem. 2020 Mar 1;189:112049.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147521/Antitumor-photosensitizer-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147521/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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