Boanmycin
Boanmycin is an antibiotic with antitumor activity that induces cellular senescence and apoptosis[1][2][3].
Product Specifications
CAS Number
37293-17-7
UNSPSC
12352005
Target
Antibiotic; Apoptosis
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boanmycin.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@]([C@H](O)C)([H])C(NCCC2=NC(C3=NC(C(NCCCNCCCCNCCCN)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O[C@]6([H])[C@H]([C@H]([C@@H]([C@H](O6)CO)O)OC(N)=O)O
Molecular Formula
C60H96N20O21S2
Molecular Weight
1497.66
References & Citations
[1]Y C Deng, et al. Activity of boanmycin against colorectal cancer. World J Gastroenterol. 2001 Feb;7 (1) :93-7.|[2]Hao Tang, et al. Effect of boanmycin on apoptosis and cell cycle of human esophageal cancer (Eca-109) cells]. Ai Zheng. 2002 Aug;21 (8) :855-9.|[3]Peng Chen, et al. The chemotherapeutic drug boanmycin induces cell senescence and senescence-associated secretory phenotype factors, thus acquiring the potential to remodel the tumor microenvironment. Anticancer Drugs. 2016 Feb;27 (2) :84-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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